Strategies For Covering the Uninsured: How California Policymakers Could Build on Lessons Learned at the Federal Level

Outlines possible health insurance coverage expansions in California that build on specific approaches from recent federal efforts

County and City Health Departments: The Need for Sustainable Funding and the Potential Effect of Health Care Reform on Their Operations

Outlines the role of local health departments, the impact of funding cuts on staff, programs, and services, and the implications for public health. Recommends securing dedicated funding sources and a central role in national healthcare reform

Gaston Memorial Hospital: Driving Quality Improvement With Data, Guidelines, and Real-Time Feedback

Describes efforts to reduce variance in provider practice patterns through data analysis and benchmarking of process-of-care measures. Discusses strategies such as sharing data, feedback, and best practices in ways physicians can utilize them immediately

Early Implementation of the Health Coverage Tax Credit in Maryland, Michigan, and North Carolina: A Case Study Summary

Examines the effectiveness of HCTCs and assesses their prospects as a model for broader reforms. Proposes reforms to improve HCTCs' ability to help current target populations and aid policymakers in designing future health insurance tax credits

COBRA Subsidies for Laid-Off Workers: An Initial Report Card

Reviews the implementation of the government subsidy of COBRA health insurance premiums for laid-off workers in the 2009 stimulus package and its effects on COBRA enrollment and medical spending. Considers policy implications for access and affordability

Federal Subsidy for Laid-Off Workers' Health Insurance: A First Year's Report Card for the New COBRA Premium Assistance

Analyzes how the subsidy for laid-off workers' costs to continue their health coverage, included in the 2009 stimulus bill, affected enrollment. Considers determining factors, implications of health reform for extending the subsidy, and lessons learned

Increasing Access: Building Working Solutions

Outlines the problem of access to basic healthcare services in the U.S. Cites local efforts to enroll people into existing insurance programs and reduce other roadblocks to care, and offers a comprehensive framework for addressing these issues

Community Voices: Lessons for National Health Policy

Highlights successful models that were designed to improve access to health care for vulnerable populations, describes ways that government can support local communities, and emphasizes the need for fundamental reform of the U.S. healthcare system

Community-Based Health Plans for the Uninsured: Expanding Access, Enhancing Dignity

Highlights community-based initiatives in Albuquerque, New Mexico; Ingham County, Michigan; El Paso, Texas; Alameda County, California; and North Carolina that have developed health plans for uninsured individuals and families

Model of ionic currents through microtubule nanopores and the lumen

It has been suggested that microtubules and other cytoskeletal filaments may act as electrical transmission lines. An electrical circuit model of the microtubule is constructed incorporating features of its cylindrical structure with nanopores in its walls. This model is used to study how ionic conductance along the lumen is affected by flux through the nanopores when an external potential is applied across its two ends. Based on the results of Brownian dynamics simulations, the nanopores were found to have asymmetric inner and outer conductances, manifested as nonlinear IV curves. Our simulations indicate that a combination of this asymmetry and an internal voltage source arising from the motion of the C-terminal tails causes a net current to be pumped across the microtubule wall and propagate down the microtubule through the lumen. This effect is demonstrated to enhance and add directly to the longitudinal current through the lumen resulting from an external voltage source, and could be significant in amplifying low-intensity endogenous currents within the cellular environment or as a nano-bioelectronic device.Comment: 43 pages, 6 figures, revised versio